Opportunity Information: Apply for PA 20 260
PHS 2020-2 is an omnibus (broad, multi-topic) SBIR funding opportunity run jointly by the National Institutes of Health (NIH), the Centers for Disease Control and Prevention (CDC), and the Food and Drug Administration (FDA). It is set up as a Parent SBIR announcement using the R43/R44 grant mechanisms, meaning it is intended to support early-stage innovation through a phased, milestone-driven research and development pathway. The overall goal is to bring in U.S. small businesses that have strong technical capabilities and can contribute directly to the R&D missions of NIH, CDC, and FDA components participating under this solicitation.
The opportunity is aimed specifically at eligible U.S. small business concerns (SBCs). In practical terms, it is for companies that meet the SBIR program rules for being a qualified small business and that can propose feasible R&D projects aligned with the participating agency components. Applications are expected to respond to defined SBIR/STTR topics and priorities, referenced in the PHS 2019-2 SBIR/STTR Program Descriptions and Research Topics for NIH, CDC, and FDA. The “omnibus” design is important because it does not focus on a single narrow problem; instead, it serves as a parent umbrella under which many health, biomedical, public health, and FDA-regulatory science related innovation topics can be proposed, as long as they fit within the missions and the listed topics.
A central restriction in this particular parent announcement is that clinical trials are not allowed. That means applicants must propose research and development that does not include a clinical trial as defined by NIH policy (for example, studies that prospectively assign human participants to interventions to evaluate effects on health-related biomedical or behavioral outcomes). Companies can still propose a wide range of preclinical work, technology development, tool building, lab validation, prototype development, and other translational activities, but they must structure the project so it stays outside the clinical trial definition and requirements.
From an eligibility standpoint, the announcement is clear that non-U.S. entities (foreign institutions) cannot apply, and non-U.S. components of U.S. organizations are also not eligible to apply. At the same time, it notes that “foreign components,” as defined in the NIH Grants Policy Statement, may be allowed in some cases. In typical NIH usage, that means a U.S. applicant organization may be able to include a discrete portion of the work performed outside the U.S. when it is well-justified (for example, a unique resource, population, specimen source, or expertise), but the applicant and awardee must still be an eligible U.S. small business and the foreign work must comply with NIH policy and approvals.
Administratively, this is a discretionary grant opportunity (not a contract), and it spans a wide set of program areas reflected by the many CFDA numbers listed (93.xxx series), which collectively cover a broad range of health and biomedical domains across NIH institutes and centers and related HHS components. The posting shows an original closing date of 2021-04-05 and a creation date of 2020-07-13, situating it within the PHS 2020-2 omnibus cycle. An award ceiling is not specified in the provided data excerpt, which is common in parent omnibus announcements because award budgets often depend on SBIR phase, topic area, institute/center policies, and the specific scope of proposed work rather than a single uniform cap.
In summary, PA 20-260 (PHS 2020-2) is a broad parent SBIR grant solicitation inviting U.S. small businesses to propose R&D projects aligned with NIH/CDC/FDA topic areas, using the SBIR R43/R44 mechanisms, with the key condition that proposed studies must not include clinical trials. It is best suited for companies developing innovative health-related technologies, products, platforms, software, diagnostics (non-clinical trial validation), research tools, and other translational capabilities that can advance federal public health and biomedical missions while remaining within the non-clinical trial scope of this announcement.Apply for PA 20 260
- The National Institutes of Health in the education, environment, food and nutrition, health, income security and social services sector is offering a public funding opportunity titled "PHS 2020-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.068, 93.070, 93.073, 93.084, 93.103, 93.113, 93.121, 93.136, 93.172, 93.173, 93.213, 93.233, 93.242, 93.262, 93.273, 93.279, 93.286, 93.307, 93.316, 93.326, 93.350, 93.351, 93.361, 93.393, 93.394, 93.395, 93.396, 93.399, 93.837, 93.838, 93.839, 93.840, 93.846, 93.847, 93.853, 93.855, 93.859, 93.865, 93.866, 93.867, 93.879.
- This funding opportunity was created on 2020-07-13.
- Applicants must submit their applications by 2021-04-05. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Small businesses.
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Applicants who have applied for this opportunity (PA 20 260) also looked into and applied for these:
| Funding Opportunity |
|---|
| PHS 2020-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed) Apply for PA 20 265 Funding Number: PA 20 265 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Successor-in-Interest (Type 6 Parent Clinical Trial Optional) Apply for PA 20 275 Funding Number: PA 20 275 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31) Apply for PA 21 051 Funding Number: PA 21 051 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) Apply for PA 21 050 Funding Number: PA 21 050 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship to Promote Diversity in Health-Related Research (Parent F31-Diversity) Apply for PA 21 052 Funding Number: PA 21 052 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions with NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) Apply for PA 21 049 Funding Number: PA 21 049 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32) Apply for PA 21 048 Funding Number: PA 21 048 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed) Apply for PAR 21 038 Funding Number: PAR 21 038 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Research Supplements to Promote Diversity in Health-Related Research (Admin Supp Clinical Trial Not Allowed) Apply for PA 21 071 Funding Number: PA 21 071 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Short Courses on Innovative Methodologies and Approaches in the Behavioral and Social Sciences (R25 - Independent Clinical Trial Not Allowed) Apply for RFA OD 21 005 Funding Number: RFA OD 21 005 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $200,000 |
| Support for Research Excellence (SuRE) Award (R16 Clinical Trial Not Allowed) Apply for PAR 21 169 Funding Number: PAR 21 169 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $100,000 |
| Support for Research Excellence First Independent Research (SuRE-First) Award (R16 - Clinical Trial Not Allowed) Apply for PAR 21 173 Funding Number: PAR 21 173 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $125,000 |
| Understanding and Addressing the Impact of Structural Racism and Discrimination on Minority Health and Health Disparities (R01 Clinical Trial Optional) Apply for RFA MD 21 004 Funding Number: RFA MD 21 004 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $500,000 |
| Academic Research Enhancement Award for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed) Apply for PAR 21 155 Funding Number: PAR 21 155 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $300,000 |
| Change of Recipient Organization (Type 7 Parent Clinical Trial Optional) Apply for PA 21 268 Funding Number: PA 21 268 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| PHS 2021-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed) Apply for PA 21 262 Funding Number: PA 21 262 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| PHS 2021-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed) Apply for PA 21 259 Funding Number: PA 21 259 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| PHS 2021-2 Omnibus Solicitation of the NIH and CDC for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required) Apply for PA 21 260 Funding Number: PA 21 260 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Limited Competition: Knockout Mouse Phenotyping Project Data Coordination Center and Database (UM1 Clinical Trial Not Allowed) Apply for RFA HG 21 037 Funding Number: RFA HG 21 037 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Limited Competition: Knockout Mouse Production and Phenotyping Project (UM1) Clinical Trial Not Allowed Apply for RFA HG 21 036 Funding Number: RFA HG 21 036 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
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